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Die Pharmazie is published by IMR Press from Volume 81 Issue 1 (2026). Previous articles were published by another publisher under the CC-BY licence, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement.

1 May 2009Research Article
Aphyllin, the first isoferulic acid glycoside and other phenolics from Tamarix aphylla flowers
M. A. M. Nawwar 1, S. A. M. Hussein 2, N. A. Ayoub 3, K. Hofmann 4, M. Linscheid 5, M. Harms 4, K. Wende 4, U. Lindequist 4
Affiliations
Article Info

1 Department of Phytochemistry, Division of Pharmaceutical Industries, National Research Center, Dokki, Egypt, mahmoudnawwar@link.net, Email: mahmoudnawwarhesham@yahoo.com

2 Department of Phytochemistry, Division of Pharmaceutical Industries, National Research Center, Dokki, Egypt

3 Faculty of Pharmacy, Department of Pharmacognosy, Ain-Shams University, Cairo, Egypt

4 Institut für Pharmazie, Pharmazeutische Biologie, Ernst-Moritz-Arndt-Universität Greifswald, Greifswald, Germany

5 Humboldt Universität zu Berlin, Berlin, Germany

Abstract

The first glycosylated isoferulic acid, isoferulic acid 3-O-β-glucopyranoside, together with the new phenolics, tamarixetin 3,3′-di-sodium sulphate and dehydrodigallic acid dimetyl ester have been characterized from a flower extract of Tamarix aphylla. The structures were established on the basis of spectral data. The extract exhibited a distinct radical scavenging effect and to improve the viability of human keratinocytes (HaCaT cells). Also, the known isoferulic acid and ferulic acid which have been determined to be the major components of the investigated extract by HPLC/ESI mass spectrometric screening have been separated, characterized and evaluated as active antioxidants and as cell activity stimulating agents as well.