Background and Purpose: White
matter hyperintensites (WMHs) , lacunes and brain atrophy have been demonstrated
to be positively related to gait disorder. However, cerebral microbleeds (CMBs)
as a manifestation of cerebral small vessel disease (CSVD) is still
under-investigated. Therefore, correlations between CMBs and
upper extremity, gait and balance performance were investigated in this study.
Methods: A cross-sectional study of middle-aged to
older adults was conducted. CSVD burden was measured with magnetic resonance
imaging (MRI) and the location and number of CMBs were analysed. Gait and balance
functions were evaluated using a four meter walkway, Tinetti,
Timed-Up-and-Go (TUG) and Short Physical Performance Battery
(SPPB) tests. Upper extremity function was measured by 10 repeated
pronation-supination time, 10 repeated finger tapping time, and 10 repeated
opening and closings of the hands. Results: A total of
224 participants were included in this study, with a mean age of 60.6
Announcements
Open Access
Original Research
Impact of Cerebral Microbleeds on Gait, Balance, and Upper Extremities Function in Cerebral Small Vessel Disease
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1
Department of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, 100020 Beijing, China
*Correspondence: wenlihu3366@126.com (Wenli Hu)
J. Integr. Neurosci. 2023, 22(4), 82;
https://doi.org/10.31083/j.jin2204082
Submitted: 2 September 2022 | Revised: 1 November 2022 | Accepted: 3 November 2022 | Published: 29 June 2023
(This article belongs to the Special Issue The Role of Imaging in the Diagnosis of Neurological Disease)
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract
Keywords
cerebral small vessel disease
cerebral microbleed
gait
balance
upper extremities
motor disturbance