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The Role of Oxidative Stress in the Induction and Development of Psoriasis
Alexander Blagov1,*, Vasily Sukhorukov1, Shuzhen Guo2, Dongwei Zhang2, Ilya Eremin3, Alexander Orekhov1,*
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1
Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia
2
Diabetes Research Center, School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, 100029 Beijing, China
3
Petrovsky National Research Centre of Surgery, 119991 Moscow, Russia
*Correspondence: al.blagov2014@gmail.com (Alexander Blagov); alexandernikolaevichorekhov@gmail.com (Alexander Orekhov)
Front. Biosci. (Landmark Ed) 2023, 28(6), 118;
https://doi.org/10.31083/j.fbl2806118
Submitted: 31 January 2023 | Revised: 31 March 2023 | Accepted: 23 May 2023 | Published: 25 June 2023
(This article belongs to the Special Issue Oxidative Stress and Mitochondrial Dysfunction)
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract
Psoriasis cannot be completely cured and is often difficult to diagnose, which is why the search for new effective therapies and diagnostics is a highly relevant area of research. To identify new therapeutic compounds, the first step is to study the role of various factors underlying the development of psoriasis. One such factor is oxidative stress. In this review, we will consider the role of oxidative stress at different stages of psoriasis development, as well as biomarkers of oxidative stress that can potentially be used in the diagnosis of psoriasis and antioxidants, which are likely to be applied in the treatment of this disease.
Keywords
psoriasis
oxidative stress
skin
Funding
# 23-45-00031/Russian Science Foundation
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