IMR Press / FBL / Volume 27 / Issue 9 / DOI: 10.31083/j.fbl2709271
Open Access Review
Identifying Human Remains from 20th Century Warfare: A State of the Field Essay
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1 Institute of Archaeological Science, Fudan University, 200433 Shanghai, China
2 MOE Key Laboratory of Contemporary Anthropology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, 200433 Shanghai, China
*Correspondence: wlx.wang@foxmail.com (Lingxiang Wang); wenshaoqing@fudan.edu.cn (Shaoqing Wen)
Academic Editor: Cristoforo Pomara
Front. Biosci. (Landmark Ed) 2022, 27(9), 271; https://doi.org/10.31083/j.fbl2709271
Submitted: 18 July 2022 | Revised: 17 August 2022 | Accepted: 31 August 2022 | Published: 29 September 2022
(This article belongs to the Special Issue Forensic pathology and forensic genetics: past, present and future)
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract

As we continually reflect on the wars of the 20th century, identification of the remains of victims takes an increasingly prominent position in ongoing research. Existing work on the identification of human remains from 20th century wars primarily covers the determination of phenotypic characteristics, kinship and geographic origins, supporting the establishment of genetic information databases. Compared with standard forensic methods, DNA analyses have revealed greater effectiveness. The process of DNA analysis includes DNA extraction, genetic marker testing and data analysis. Protocols from ancient DNA research can be applied to degraded remains, and next-generation sequencing (NGS) techniques can compensate for shortcomings in the most commonly-used PCR-capillary electrophoresis typing. As it stands, wide-ranging inter-governmental and inter-institutional collaboration is necessary in order to set up NGS-based public databases, and thereby promote the identification of human remains and archaeological forensics.

Keywords
forensic science
physical anthropology
degraded samples
STR typing
next-generation sequencing
Funding
32070576/National Natural Science Foundation of China
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