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Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

1 Jan 2017Review

Advances in the treatment of rotator cuff lesions by cytokines

Genbin Wu 1, PengCheng Xu 1, Peng Wu 1, Kaihua Hu 1, Yeqing Sun 1, Biao Cheng 1,*, Yong Lu 2
Affiliations
Article Info

1 Department of Orthopedics, Shanghai Tenth People’s Hospital, Tongji University, School of Medicine, ZhabeiArea, Shanghai 200072, China

2 Department of Radiology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China

Abstract

Rotator cuff tear is one of the most common shoulder injuries, often requiring surgical intervention, including options such as suture repair, autografts, allografts, and synthetic prostheses. While surgery can significantly improve outcomes, an ideal therapeutic strategy has not been found. Often, injuries respond poorly and require prolonged rehabilitation. Recent attention has been focused on biologic pathways which can augment tendon healing, consequently leading to the identification of growth factors. Herein, we review growth factors and their roles in rotator cuff healing.

Keywords

  • Rotator Cuff Lesion
  • Cytokines
  • Rotator Cuff Healing
  • TGF-beta
  • Review

References