IMR Press / FBL / Volume 21 / Issue 5 / DOI: 10.2741/4436

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review

Role of microRNAs in the metastasis of non-small cell lung cancer

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1 Department of Pathology, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China
2 Department of Oncology, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China
3 Department of Interventional Therapy, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China
Academic Editor:Wei Qin
Front. Biosci. (Landmark Ed) 2016, 21(5), 998–1005; https://doi.org/10.2741/4436
Published: 1 June 2016
Abstract

Lung cancer is the leading cause of cancer death. Non-small cell lung cancer (NSCLC), including the squamous cell carcinoma, large cell carcinoma and adenocarcinoma subtypes, accounts for more than 80% of primary lung cancer cases. Understanding the mechanisms underlying NSCLC metastasis is essential for the improvement of anticancer therapies. Recent studies have shown that microRNAs (miRNAs) play very important roles in the progression of NSCLC from its initial stages to metastasis. This review discusses these central roles of miRNAs in the NSCLC metastasis.

Keywords
Non-Small Cell Lung Cancer
MicroRNAs
Metastasis
Review
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