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Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

1 Jun 2016Review
Inflammation and endometriosis
Lingli Jiang 1, Yan Yan 2, Zhou Liu 1,*, Ying Wang 1
Affiliations
Article Info

1 Department of Obstetrics and Gynecology, Zhou Pu Hospital, Shanghai, China

2 Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, Shanghai 200040, China

Abstract

Endometriosis is defined by presence of endometrial glands and stroma outside the uterine cavity and it affects approximately 5%–10% of women of reproductive age. Although endometriosis is usually considered to be due to retrograde menstruation, the true pathogenesis of this disease remains poorly understood. Endometriosis is associated with an inflammatory response and this inflammation leads to endothelial dysfunction and might even lead to carcinogenesis. Here, we review our current understanding of the role of inflammatory processes in the pathogenesis of endometriosis.

Keywords

  • Endometrium
  • Endometriosis
  • Inflammation
  • RANTES
  • Review

References