IMR Press / FBL / Volume 21 / Issue 5 / DOI: 10.2741/4431

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review

Inflammation and endometriosis

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1 Department of Obstetrics and Gynecology, Zhou Pu Hospital, Shanghai, China
2 Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, Shanghai 200040, China
Academic Editor:Fei He
Front. Biosci. (Landmark Ed) 2016, 21(5), 941–948; https://doi.org/10.2741/4431
Published: 1 June 2016
(This article belongs to the Special Issue Cellular immunology and stem cell biology)
Abstract

Endometriosis is defined by presence of endometrial glands and stroma outside the uterine cavity and it affects approximately 5%–10% of women of reproductive age. Although endometriosis is usually considered to be due to retrograde menstruation, the true pathogenesis of this disease remains poorly understood. Endometriosis is associated with an inflammatory response and this inflammation leads to endothelial dysfunction and might even lead to carcinogenesis. Here, we review our current understanding of the role of inflammatory processes in the pathogenesis of endometriosis.

Keywords
Endometrium
Endometriosis
Inflammation
RANTES
Review
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