IMR Press / FBL / Volume 20 / Issue 6 / DOI: 10.2741/4345

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review
Platelet activation is a key event in the pathogenesis of streptococcal infections
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1 Department of Blood Transfusion, Southwest Hospital, The Third Military Medical University, China
2 Institute of Infectious Diseases of Chinese PLA, Southwest Hospital, Third Military Medical University, China
Academic Editor:Fei He
Front. Biosci. (Landmark Ed) 2015, 20(6), 910–918; https://doi.org/10.2741/4345
Published: 1 June 2015
(This article belongs to the Special Issue Cellular immunology and stem cell biology)
Abstract

Diverse Streptococcus species including Streptococcus Pneumoniae, Sanguis, Gordonii, Mitis and Mutans cause life-threatening conditions including pneumonia, bacteremia and meningitis. These diseases bear a high morbidity and mortality and for this reason, understanding the key events in the pathogenesis of these infections have a great significance in their prevention and/or treatment. Here, we describe as how the activation of the platelets and their affinity to bind to bacterial proteins act as early key events in the pathogenesis of Streptococcal infections.

Keywords
Streptococcus
Platelets
Infection
Review
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