IMR Press / FBL / Volume 20 / Issue 6 / DOI: 10.2741/4345

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Platelet activation is a key event in the pathogenesis of streptococcal infections
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1 Department of Blood Transfusion, Southwest Hospital, The Third Military Medical University, China
2 Institute of Infectious Diseases of Chinese PLA, Southwest Hospital, Third Military Medical University, China
Academic Editor:Fei He
Front. Biosci. (Landmark Ed) 2015, 20(6), 910–918;
Published: 1 June 2015
(This article belongs to the Special Issue Cellular immunology and stem cell biology)

Diverse Streptococcus species including Streptococcus Pneumoniae, Sanguis, Gordonii, Mitis and Mutans cause life-threatening conditions including pneumonia, bacteremia and meningitis. These diseases bear a high morbidity and mortality and for this reason, understanding the key events in the pathogenesis of these infections have a great significance in their prevention and/or treatment. Here, we describe as how the activation of the platelets and their affinity to bind to bacterial proteins act as early key events in the pathogenesis of Streptococcal infections.

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