IMR Press / FBL / Volume 19 / Issue 5 / DOI: 10.2741/4244

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review
A review of maternally inherited diabetes and deafness
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1 Institute for Integrated Traditional and WesternMedicine, the Second Affiliated Hospital of Xingtai Medical College, Xingtai,054000, Hebei Province, China
2 Department of Health, Hotan Detachment of the Xinjiang Armed Police Corps, Hotan 848011, Xinjiang Uygur Autonomous Region, China
Academic Editor:Fei He
Front. Biosci. (Landmark Ed) 2014, 19(5), 777–782;
Published: 1 January 2014
(This article belongs to the Special Issue Cellular immunology and stem cell biology)

Maternally inherited diabetes and deafness (MIDD), a mitochondrial disease first described in 1992, results from the mitochondrial DNA mutation and affects up to 1% of the patients with diabetes. This review discusses the biomedical mechanisms of MIDD patients; summarizes the recent improvement of clinical and genetic diagnosis of MIDD; outlines the advances of the clinical management of these patients and their families.

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