IMR Press / FBL / Volume 18 / Issue 1 / DOI: 10.2741/4098

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Review
The power of yeast to model diseases of the powerhouse of the cell
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1 Department of Physiology, Johns Hopkins School of Medicine, Baltimore, MD 21205-2185, USA
Front. Biosci. (Landmark Ed) 2013, 18(1), 241–278; https://doi.org/10.2741/4098
Published: 1 January 2013
Abstract

Mitochondria participate in a variety of cellular functions. As such, mitochondrial diseases exhibit numerous clinical phenotypes. Because mitochondrial functions are highly conserved between humans and Saccharomyces cerevisiae, yeast are an excellent model to study mitochondrial disease, providing insight into both physiological and pathophysiological processes.

Keywords
Mitochondria
Oxidative Phosphorylation
Mitochondrial Disease
Saccharomyces cerevisiae
Review
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