IMR Press / FBL / Volume 17 / Issue 6 / DOI: 10.2741/4056

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Role of miR-155 in breast cancer
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1 Department of Surgery, Hushan Hospital, Fudan University, Shanghai, China
Front. Biosci. (Landmark Ed) 2012, 17(6), 2350–2355;
Published: 1 June 2012
(This article belongs to the Special Issue Pathogenesis and diagnostic modalities in cancer)

Breast cancer is the second leading cause of death due to cancer in women. Accumulating evidence shows a correlation between overexpression of miR-155 and breast cancer development. The microRNA (miRNA) encoded by mir-155 is known to be oncogenic in multiple tumors. This review summarizes the signaling pathways that are regulated by miR-155 in breast cancer and discusses therapeutic possibilities related to miR-155.

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