IMR Press / FBL / Volume 16 / Issue 5 / DOI: 10.2741/3825

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Effects of omega-3 polyunsaturated fatty acids on cardiac myocyte protection
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1 Department of Experimental Medicine and Biochemical Sciences, University of Rome, Tor Vergata, Rome, Italy.
2 Department of Cardiac Surgery, IRCSS Policlinico, S. Donato, S. Donato Milanese, Milan, Italy
3 Department of Experimental Medicine, University of Rome, Sapienza, Rome, Italy
4 Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, Catania, Italy

Academic Editor: Fabio Galvano

Front. Biosci. (Landmark Ed) 2011, 16(5), 1833–1843;
Published: 1 January 2011
(This article belongs to the Special Issue Dietary approaches to prevent chronic-degenerative diseases)

Many epidemiologic, observational and randomized human clinical trials have demonstrated beyond doubt the protective cardiovascular effects of omega-3 polyunsaturated fatty acids (PUFAs). Cardiac myocytes protection by omega-3 PUFAs involves several mechanisms which might have a synergistic effect. This review provides a summary of the in vitro and in vivo effects of omega-3 PUFAs on cardiac myocytes health and reports the outcome of a number of clinical trials in patients consuming omega-3 PUFAs.

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