IMR Press / FBL / Volume 14 / Issue 12 / DOI: 10.2741/3554

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Animal models of smoke inhalation induced injuries
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1 Combat Care Laboratory, Combat Care and Performance Programme, Defence Medical & Environmental Research Institute, DSO National Laboratories (Kent Ridge), 27 Medical Drive #09-01, Singapore 117510

Academic Editor: Madhav Bhatia

Front. Biosci. (Landmark Ed) 2009, 14(12), 4618–4630;
Published: 1 January 2009
(This article belongs to the Special Issue Animals in SIRS research)

Smoke inhalation injury is the leading cause of mortality from structural fires, as a result of complications such as systemic inflammatory response syndrome and chronic obstructive pulmonary disease, which can be caused by a localized or systemic response. In this review, the pathophysiology of smoke inhalation injury, along with the characteristics found in clinical settings, common animal models, current treatment methods and future potential therapeutics are discussed.

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