IMR Press / FBL / Volume 14 / Issue 1 / DOI: 10.2741/3241

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Stromal cells
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1 CNRS UMR 6600, Technological University of Compiegne, BP 20529 60205 Compiegne Cedex, France
Academic Editors:Patrick Vermette, Jonathan Lakey, Rennian Wang, Steven Paraskevas
Front. Biosci. (Landmark Ed) 2009, 14(1), 210–224;
Published: 1 January 2009

Stromal cells, or mesenchymal stem cells, are adherent clonogenic cells that can form colonies. They are mainly isolated from bone marrow but can also be found in umbilical cord blood, adipose tissues and amniotic fluids. These stem cells are easy to culture in vitro, and can differentiate into osteoblasts, chondrocytes, or adipocytes when stimulated appropriately. When seeded on a natural (titanium, ceramics, collagen fibers, silk, etc.) or synthetic (PLLA, PLGA, etc.) biomaterial scaffold, they adhere and differentiate to form a new tissue. Many studies have also explored stromal cell differentiation in bioreactors to form a 3-dimensional culture. This review focuses on the biomaterials used for tissue engineering with stromal cells.

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