IMR Press / FBL / Volume 13 / Issue 4 / DOI: 10.2741/2779

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Molecular imaging as the main part of our decision-making and treatment strategies in stroke
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1 Department of Radiology Molecular Imaging Program at Stanford (MIPS) and Bio-X Program, Stanford University School of Medicine, CA
2 Department of Neurosurgery, Stanford Stroke Center, Stanford, CA
Front. Biosci. (Landmark Ed) 2008, 13(4), 1535–1556;
Published: 1 January 2008

Review of results of clinical studies indicates the number of potential patients who are actually treated for acute ischemic stroke is disappointingly low, and effective treatments are making a minor impact on this major public health problem. Imaging modalities, such as diffusion- and perfusion-weighted images, as well as CT perfusion and CT angiography, to better select patients for treatment are now routinely performed in most academic medical centers. However, there is not a perfect penumbra imaging technique and each one has its own advantages and disadvantages. Recent advances in molecular imaging modalities allow a better understanding of this pathophysiological process that could lead to enhanced therapy for stroke. This article seeks to describe the role of molecular imaging in identifying the pathophysiology of stroke and how it could be incorporated in future decision-making and treatment strategies in stroke.

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