Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.
1 Epithelial Stem Cell Biology Laboratory, Peter MacCallum Cancer Centre, St Andrew’s Place, East Melbourne, Victoria 3002, Australia
2 Bernard O'Brien Institute of Microsurgery, 42 Fitzroy Street, Fitzroy 3065, Australia
Abstract
Our understanding of adult epidermal stem cells has increased substantially over the last two decades especially; however even more detailed knowledge is imperative for realizing potential medical therapies. We need to know how to identify these cells and what regulates their function. In this review, we describe the literature to date and elucidate the clinical relevance of these findings.