IMR Press / FBE / Volume 14 / Issue 1 / DOI: 10.31083/j.fbe1401001
Open Access Review
Autism and associated disorders: cannabis as a potential therapy
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1 Department of Biomedical and Pharmaceutical Sciences, Touro College of Pharmacy, New York, NY 10027, USA
2 Department of Medicinal Chemistry, School of Pharmacy, College of Health Sciences, Mekelle University, 231 Tigray, Ethiopia
3 Department of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY 10595, USA

Academic Editor: Igor Lavrov

Front. Biosci. (Elite Ed) 2022 , 14(1), 1; https://doi.org/10.31083/j.fbe1401001
Submitted: 25 October 2021 | Revised: 23 November 2021 | Accepted: 10 December 2021 | Published: 13 January 2022
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract

Autism spectrum disorder (ASD) is a group of disabilities with impairments in physical, verbal, and behavior areas. Regardless the growing frequency of autism, no medicine has been formed for the management of the ASD primary symptoms. The most frequently prescribed drugs are off-label. Therefore, there is necessity for an advance tactic for the treatment of autism. The endocannabinoid system has a central role in ruling emotion and social behaviors. Dysfunctions of the system donate to the behavioral deficits in autism. Therefore, the endocannabinoid system represents a potential target for the development of a novel autism therapy. Cannabis and associated compounds have produced substantial research attention as a capable therapy in neurobehavioral and neurological syndromes. In this review we examine the potential benefits of medical cannabis and related compounds in the treatment of ASD and concurrent disorders.

Keywords
Autism
Endocannabinoid system
Medical cannabis
CBD
THC
CBDV
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