IMR Press / CEOG / Volume 52 / Issue 3 / DOI: 10.31083/CEOG26808
Open Access Original Research
Investigating the Link Between Poor Sleep Patterns and Type 2 Diabetes Mellitus in Women With a History of Gestational Diabetes Mellitus: A Retrospective Population-Based Study
Yizheng Zu1,2,3,4,5,†Xia Xu1,2,3,4,5,†Xiaoyan Xiu1,2,3,4,5,†Yi Xie1,2,3,4,5Huangchang Yi1,2,3,4,5Lianghui Zheng1,2,3,4,5Jianying Yan1,2,3,4,5,*
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Affiliation
1 Fujian Maternity and Child Health Hospital, 350001 Fuzhou, Fujian, China
2 College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, 350001 Fuzhou, Fujian, China
3 Fujian Clinical Research Center for Maternal-Fetal Medicine, 350001 Fuzhou, Fujian, China
4 Laboratory of Maternal-Fetal Medicine, Fujian Maternity and Child Health Hospital, 350001 Fuzhou, Fujian, China
5 National Key Obstetric Clinical Specialty Construction Institution of China, 350001 Fuzhou, Fujian, China
*Correspondence: yanjy2019@fjmu.edu.cn (Jianying Yan)
These authors contributed equally.
Clin. Exp. Obstet. Gynecol. 2025, 52(3), 26808; https://doi.org/10.31083/CEOG26808
Submitted: 1 October 2024 | Revised: 23 January 2025 | Accepted: 27 January 2025 | Published: 5 March 2025
(This article belongs to the Special Issue Obstetric Management of High-Risk Pregnancy)
Copyright: © 2025 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract
Background:

This study aimed in this study was to investigate the association between poor sleep patterns (PSPs) and type 2 diabetes mellitus (T2DM) in women with a history of gestational diabetes mellitus (GDM).

Methods:

Our analysis was based on a population-based sample from National Health and Nutrition Examination Survey (NHANES) data collected between 2007 and 2018. The association between PSPs and T2DM in women with a history of GDM was assessed using logistic regression models. We performed subgroup analyses stratified by age, body mass index (BMI), race, educational level, moderate recreational activities, smoking behavior, and parity.

Results:

A total of 917 women with a history of GDM were included in our study. Compared to the non-PSPs group, participants with PSPs had a higher possibility for T2DM in women with a history of GDM (odds ratio (OR) = 2.37, 95% confidence interval (CI): 1.45–3.86). Furthermore, this association was more prominent in those aged between 35 and 49 (OR = 2.20, 95% CI: 1.03–4.71), a BMI ≥30 kg/m2 (OR = 2.56, 95% CI: 1.43–4.60), non-Hispanic white (OR = 5.34, 95% CI: 2.09–13.66) or non-Hispanic black (OR = 5.02, 95% CI: 1.48–17.06), educated beyond high school (OR = 2.65, 95% CI: 1.35–5.23), not engaged in moderate recreational activities (OR = 3.25, 95% CI: 1.72–6.14) groups and parity ≥4 (OR = 2.62, 95% CI: 1.03–6.63).

Conclusions:

Our findings suggest that PSPs are positively associated with the prevalence of T2DM in women with a history of GDM, which demonstrates that we need targeted interventions, especially for those at high risk. Future research should evaluate how sleep patterns affect metabolic health and develop new ways to lower the risk of T2DM in women with a history of GDM.

Keywords
poor sleep pattern
gestational diabetes mellitus
type 2 diabetes mellitus
women
NHANES
Funding
2020Y9134/ Joint Funds for the innovation of science and Technology
2020GGA021/ Fujian Provincial Health Technology Project
2024ZD01005/ Fujian Provincial Health Technology Project
National Key Clinical Specialty Construction Program of China (Obstetric)
2024Y0035/ Fujian Provincial Natural Science Foundation of China
Figures
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