- Academic Editor
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†These authors contributed equally.
Background: The aim of this study was to investigate the effects of
intravenous immunoglobulins (IVIg) in the immunotherapy of in vitro
fertilization and embryo transfer (IVF-ET) patients and to provide insights into
the treatment strategy for implantation failure. Methods: A
retrospective observational study of 245 patients with unexplained repeated
implantation failure in our hospital from 2016 to 2021 was conducted. Among these
patients, 124 were administered IVIg according to their preferences during the
preparation of implantation, while the others were not given IVIg as a control
group. The basic characteristics of the patients in the two groups did not show
any significant differences. Biochemical pregnancy rate, clinical pregnancy rate,
and live birth rate were compared in the two groups, and also in the IVIg group
and the control group, by age (