IMR Press / CEOG / Volume 50 / Issue 6 / DOI: 10.31083/j.ceog5006120
Open Access Original Research
Impact of Coronavirus Disease 2019 in Cesarean Delivery and Neonates: A Case-Control Study
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1 Department of Obstetrics and Gynecology, Gyeongsang National University Changwon Hospital, 51472 Changwon, Republic of Korea
2 Department of Obstetrics and Gynecology, Gyeongsang National University School of Medicine, 52828 Jinju, Republic of Korea
3 Institute of Health Science, Gyeongsang National University, 52828 Jinju, Republic of Korea
*Correspondence: cholida73@naver.com (Hyen Chul Jo)
Clin. Exp. Obstet. Gynecol. 2023, 50(6), 120; https://doi.org/10.31083/j.ceog5006120
Submitted: 29 March 2023 | Revised: 19 April 2023 | Accepted: 24 April 2023 | Published: 30 May 2023
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract

Background: The aim of this study was to compare the maternal, surgical, and neonatal outcomes in pregnant women with coronavirus disease 2019 (COVID-19) who underwent cesarean delivery at term and provide evidence for the management of parturient with COVID-19. Methods: This case-control study was conducted retrospectively and evaluated 67 cases of cesarean delivery between February 1 and May 31 performed at the Gyeongsang National University Changwon Hospital, Korea. Case group included women who had positive reverse transcriptase-polymerase chain reaction (RT-PCR) test within 7 days before delivery. Control group was selected based on mode of delivery and gestational age among women with negative RT-PCR result. Results: A total of 34 women with COVID-19 and 33 COVID-19-negative women and their neonate were included in this study. Preoperative C-reactive protein was higher in case group (6.4 mg/L vs 1.8 mg/L, p < 0.001), but preoperative and postoperative day 1 and 3 hemoglobin levels did not differ between groups. Postoperative complications were similar in both groups. Control group had higher 1- and 5-minute APGAR scores than case group (p = 0.006 and p = 0.005) and showed better results of cord blood analyses in cord blood pH and base deficit (p = 0.001 and p = 0.002). Neonatal admission to intensive care unit did not differ between groups and there was no vertical transmission of COVID-19. Conclusions: Pregnant women with coronavirus disease 2019 at term who underwent urgent cesarean delivery showed comparable surgical and neonatal outcomes except higher preroperative C-reactive protein levels compared to COVID-19-negative women.

Keywords
COVID-19
cesarean delivery
pregnancy
neonate
SARS-CoV-2
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