IMR Press / CEOG / Volume 49 / Issue 4 / DOI: 10.31083/j.ceog4904085
Open Access Case Report
Peutz-Jeghers syndrome a review of gynecological implications and the management of these patients through the presentation of a case report
Show Less
1 Hipolit Cegielski State University of Applied Sciences, 62-200 Gniezno, Poland
2 Division of Developmental Gynaecology and Sexology, Department of Perinatology and Gynaecology, Poznań University of Medical Sciences, 60-535 Poznan, Poland
3 Faculty of Medicine, Collegium Medicum, Cardinal Stefan Wyszyński University, 01-938 Warsaw, Poland
4 Department of Newborns' Infectious Diseases, Poznan University of Medical Sciences, 60-535 Poznan, Poland
5 Department of Dietetics, Poznan University of Physical Education, Faculty of Physical Culture in Gorzów Wielkopolski, 61-871 Poznań, Poland
6 Departament of Organization and Management in Heathcare, Organization and Management in Healthcare, Faculty of Health Sciences, Poznan University of Medical Sciences, 60-001 Poznań, Poland
7 Science Students Circle, Institute of Health Sciences, Hipolit Cegielski State University of Applied Sciences, 62-200 Gniezno, Poland
*Correspondence: plagens.rotman@gmail.com (Katarzyna Plagens-Rotman)
Academic Editor: Michael H. Dahan
Clin. Exp. Obstet. Gynecol. 2022, 49(4), 85; https://doi.org/10.31083/j.ceog4904085
Submitted: 1 September 2021 | Revised: 21 October 2021 | Accepted: 29 October 2021 | Published: 8 April 2022
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract

Background: Peutz-Jeghers Syndrome (PJS) is a rare autosomal dominant genetic condition caused by mutations in STK11 (Serine/threonine kinase 11) gene (OMIM 602216 Serine/Threonine Protein Kinase 11) located in the short arm of chromosome 19 (19p.13.3). Case: We report the case of a 4 and ½ year-old female child with a rare Peutz-Jeghers Syndrome. She was admitted to the Clinic of Gynaecology, the Faculty of Perinatology and Gynaecology, Chair of Adolescence Gynaecology and Sexology at Poznan University of Medical Sciences, in order to undergo preventive medical examinations. The patient was accompanied by her mother. Age and sex-appropriate development. Age-appropriate dental condition. Gynaecological examination was conducted. No changes were identified through palpation. Normal ultrasound picture. No symptoms of genital mucosa estrogenization, which is typical of the patient’s age. A small amount of vaginal discharge was found. Pap smear was conducted to assess vaginal biocenosis. Lacidobacilli deficiency was found and feminine hygiene products, such as Iladian, were recommended. Melanotic macules around the mouth, typical of Peutz-Jeghers Syndrome were identified. Conclusions: Due to the increased cancer risk in patients with Peutz-Jeghers Syndrome, more frequent medical and gynaecological examinations are recommended for the girl. It should be noted that the girl’s mother decision to have her daughter examined at such a young age was appropriate.

Keywords
Children
Polyposis
Peutz-Jeghers syndrome
Share
Back to top