IMR Press / CEOG / Volume 49 / Issue 1 / DOI: 10.31083/j.ceog4901024
Open Access Original Research
Diagnostic accuracy of hysteroscopy vs dilation and curettage (D&C) for atypical endometrial hyperplasia in patients performing hysterectomy or serial follow-up
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1 Department of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, Italy
2 Department of Surgical Sciences, Division of Gynecology and Obstetrics, University of Cagliari, 09124 Cagliari, Italy
3 Department of Medical Sciences, Section of Obstetric and Gynaecology, University of Ferrara, 44121 Ferrara, Italy
4 Department of Obstetrics and Gynecology, Institute for Maternal and Child Health IRCCS ``Burlo Garofolo'', 34137 Trieste, Italy

Academic Editor: Michael H. Dahan

Clin. Exp. Obstet. Gynecol. 2022, 49(1), 24;
Submitted: 27 July 2021 | Revised: 25 September 2021 | Accepted: 26 September 2021 | Published: 18 January 2022
(This article belongs to the Special Issue Updates in Obstetrics and Gynecology)
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.

Background: Endometrial hyperplasia (EH) is considered a heterogeneous pre-neoplastic clinical entity characterized by an abnormal glandular proliferation, with less than half of the tissue area occupied by the stroma. The aim of this retrospective study was to evaluate the correlation between the histological diagnosis of atypical endometrial hyperplasia (AEH) obtained through office hysteroscopy (OH) or uterine dilation and curettage (D&C) and the definitive histological evaluation after hysterectomy. Methods: Among 112 patients with atypical EH, 45 (40%) underwent hysteroscopy and 67 (60%) curettage. Results: The diagnostic accuracy of OH was very high: in particular, it showed a diagnostic coincidence in 87% of cases with the definitive histological diagnosis through hysteroscopy. The curettage, instead, had diagnostic coincidence only in 14% of cases. Conclusion: Office hysteroscopy is the ideal procedure for both diagnosis and follow-up of endometrial hyperplasia.

Endometrial hyperplasia (EH)
Office hysteroscopy (OH)
Dilation and curettage (D&C)
Transvaginal ultrasound (TVUS)
Endometrial biopsy (EB)
Endometrial carcinoma
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