Dear Colleagues,

Large-scale brain networks, such as the Default Mode Network (DMN), the Salience Network (SN), and the Frontoparietal/Central Executive Network (FPN/CEN), represent core dimensions of human cognition and psychopathology. Although widely studied through static connectivity, emerging evidence supports a dynamic view in which temporal, frequency-specific, and directed interactions govern network function across cognitive states.

In healthy adults, dynamic coordination among default, salience, and control networks undermines attention, working memory, cognitive flexibility, and internally oriented thought. Alterations in these temporal dynamics also characterize neurodevelopmental disorders, psychiatric conditions, normative aging, and neurodegenerative diseases, with measurable alterations in functional connectivity and network modulation impacting behavior and clinical outcomes.

Multimodal neuroimaging integrating EEG, fMRI, intracranial recordings, and computational approaches reveals how oscillatory and effective connectivity patterns vary across individuals, tasks, and clinical populations. This Special Issue of the Journal of Integrative Neuroscience invites contributions that advance temporally informed, multimodal frameworks of brain networks in typical adult cognition, as well as across developmental, aging, and clinical contexts. Submissions should bridge spatial, functional, and temporal levels of analysis and clarify implications for cognitive function, translational biomarkers, and models of brain health and disease.

Prof. Dr. Amedeo D'Angiulli
Guest Editor