IMR Press / FBL / Volume 26 / Issue 8 / DOI: 10.52586/4950
Open Access Review
Kinesin superfamily proteins: roles in osteosarcoma
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1 School of Basic Medicine, Gannan Medical University, 341000 Ganzhou, Jiangxi, China
2 Independent researcher, No.93-1 Xuefu road, Jingkou district, 212001 Zhenjiang, Jiangsu, China
*Correspondence: (Gaolu Cao); (Panpan Huang)
Front. Biosci. (Landmark Ed) 2021, 26(8), 370–378;
Submitted: 9 June 2021 | Revised: 4 July 2021 | Accepted: 9 July 2021 | Published: 30 August 2021
Copyright: © 2021 The Author(s). Published by BRI.
This is an open access article under the CC BY 4.0 license (

Background: Osteosarcoma is a common bone tumor with extremely high malignancy, occurring mostly in children and adolescents. At present, the survival rate of osteosarcomas has made progress in some aspects; however, this can only be regarded as a partial success because substantial progress has not been made in the last few decades. Object: The kinesin superfamily is a group of proteins that play regulatory roles in various metabolic processes and are closely related to tumor metastasis. Increasing evidence shows that kinesins play key roles in the occurrence and development of human cancer. Purpose: This review summarizes the roles of the kinesin superfamily proteins in osteosarcoma and related functions.

Kinesin superfamily
Fig. 1.
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