Revista de Neurología (RN) is published by IMR Press from Volume 79 Issue 11 (2024). Previous articles were published by under the CC-BY-NC-ND licence, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement.
1 Instituto de Investigación Sanitaria Biogipuzkoa, Donostia-San Sebastián, España
2 Athenea Neuroclinics, Donostia-San Sebastián, España
3 Hospital Universitario Donostia-Osakidetza, Donostia-San Sebastián, España
4 Universidad de Deusto, Donostia-San Sebastián, España
5 Hospital Reina Sofía, Tudela, España
6 Instituto de Investigación Sanitaria Aragón, Zaragoza, España
7 Hospital Universitario de La Princesa, Madrid, España
8 Hospital Universitario y Politécnico La Fe, Valencia, España
9 Instituto de Investigación Sanitaria La Fe, Valencia, España
10 Hospital Universitario de Albacete, Albacete, España
11 Hospital de la Santa Creu i Sant Pau, 08025 Barcelona, España
12 Universidad de Navarra, Pamplona, España
*Correspondencia: Dra. Ane Mínguez-Olaondo. Servicio de Neurología. Hospital Universitario Donostia-Osakidetza. Begiristain Doktorea Pasealekua, s/n. E-20014. Donostia, España.
E-mail: aminguezolaondo@gmail.com
Abstract
Treatment of migraine attacks is advised in all patients, using non-steroidal anti-inflammatory drugs when the pain is mild and triptans when the pain intensity is moderate-severe. However, the effectiveness of these drugs is moderate, a high percentage of patients have side effects, and triptans are contraindicated in people with a history of stroke, ischaemic heart disease or poorly controlled hypertension. Hence, there is an urgent need for new therapeutic alternatives. In recent years, new drugs for migraine attacks have become available, most notably ditans (lasmiditan) and gepants (ubrogepant and rimegepant). Furthermore, eptinezumab, which has been approved for the preventive treatment of migraine in adults, has also been used for migraine attacks. This manuscript reviews the efficacy and safety results of the new drugs for migraines that will soon be on the market.
Keywords
- Eptinezumab
- Lasmiditan
- Migraine
- Rimegepant
- Treatment
- Ubrogepant
