Background: Cardiac rehabilitation (CR) is essential in reducing
cardiovascular mortality and morbidity. High-intensity interval training (HIIT)
has emerged as a promising exercise intervention for enhancing clinical outcomes
in cardiac patients. This study aimed to investigate the effects of two
short-term exercise-based programs employing HIIT and moderate-intensity
continuous training (MICT) in comparison to a control group concerning blood
pressure, body composition, and blood biomarkers in patients diagnosed with
coronary artery disease (CAD). Methods: Seventy-two CAD patients (14%
women) underwent randomization into three groups: HIIT, MICT, and control. The
training programs encompassed six weeks of supervised treadmill exercises,
conducted thrice weekly. MICT targeted
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Open Access
Original Research
Effects of High-Intensity Interval Training vs Moderate-Intensity Continuous Training on Body Composition and Blood Biomarkers in Coronary Artery Disease Patients: A Randomized Controlled Trial
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1
Departamento de Desporto e Saúde, Escola de Saúde e Desenvolvimento Humano, Universidade de Évora, 7000-727 Évora, Portugal
2
Comprehensive Health Research Centre, 7002 - 554 Évora, Portugal
3
Department of Cardiology, Santa Maria Hospital, 1649-028 Lisbon, Portugal
4
Department of Cardiology, Espírito Santo Hospital of Évora, 7000-811 Évora, Portugal
*Correspondence: cjg@uevora.pt (Catarina Gonçalves)
Rev. Cardiovasc. Med. 2024, 25(3), 102;
https://doi.org/10.31083/j.rcm2503102
Submitted: 28 August 2023 | Revised: 18 October 2023 | Accepted: 27 October 2023 | Published: 11 March 2024
(This article belongs to the Special Issue Current Role and Future Perspectives of Cardiac Rehabilitation in Heart Disease)
Copyright: © 2024 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract
Keywords
cardiovascular disease
cardiovascular risk factors
clinical trials
high-intensity interval training
randomized controlled trial
Graphical Abstract
Funding
UIDB/04923/2020/National funds through the Foundation for Science and Technology
SFRH/BD/138326/2018/Doctoral fellowship
Figures
Fig. 1.