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Abdominal Aortic Aneurysm and PET/CT: From Molecular Mechanisms to Potential Molecular Imaging Targets
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1
Department of General Surgery (Vascular Surgery), The Affiliated Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China
2
Department of Neurology, The Affiliated Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China
3
The State Key Laboratory of Quality Research in Chinese Medicine of Macau University of Science and Technology, Avenida Wai Long, 999078 Taipa, Macau
4
Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, (Collaborative Innovation Center for Prevention of Cardiovascular Diseases) Institute of Cardiovascular Research, Southwest Medical University, 646000 Luzhou, Sichuan, China
5
Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, The Affiliated Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China
*Correspondence: lyong74@sina.com (Yong Liu); wwm1121@swmu.edu.cn (Weiming Wang)
†These authors contributed equally.
§These authors contributed equally.
†These authors contributed equally.
§These authors contributed equally.
Rev. Cardiovasc. Med. 2023, 24(5), 132;
https://doi.org/10.31083/j.rcm2405132
Submitted: 13 November 2022 | Revised: 23 December 2022 | Accepted: 3 January 2023 | Published: 27 April 2023
(This article belongs to the Special Issue Promising Novel Biomarkers in Cardiovascular Diseases)
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract
Abdominal aortic aneurysm (AAA) is the most common and critical aortic disease. Bleeding is the most serious complication from a ruptured AAA, which often results in death. Therefore, early diagnosis and treatment are the only effective means to reduce AAA associated mortality. Positron emission tomography/computed tomography (PET/CT) combines functional and anatomical imaging. The expanded application of PET/CT in the medical field could have benefits for the diagnosis and treatment of patients with AAA. This review explores the efficiency of PET/CT in the diagnosis of AAA based on our understanding of the underlying molecular mechanisms of AAA development.
Keywords
PET/CT
abdominal aortic aneurysm
molecular mechanism
molecular imaging
review
Funding
2021-JYJ-57/Luzhou Science and Technology Plan Project
HYX22002/Open Program of Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province
KeyME-2020-008/Open Fund of the Key Laboratory of Medical Electrophysiology of Ministry of Education and Sichuan Province
Figures
Fig. 1.