Background: Aortic stenosis (AS) is the world’s most prevalent heart
valve disease. Transcatheter aortic valve replacement (TAVR) or Implantation
(TAVI) is widely available yet adopting this procedure in Asia has been slow due
to high device cost, the need for specific training programs, and the lack of
specialized heart teams and dedicated infrastructures. The limited number of
randomized controlled trials describing TAVI outcomes among the Asian population
hampered the approval for medical reimbursements as well as acceptance among
surgeons and operators in some Asian countries. Methods: A comprehensive
medical literature search on TAVI and/or TAVR performed in Asian countries
published between January 2015 and June 2022 was done through MEDLINE and manual
searches of bibliographies. The full text of eligible articles was obtained and
evaluated for final analysis. The event rates for key efficacy and safety
outcomes were calculated using the data from the registries and randomized
controlled trials. Results: A total of 15,297 patients were included
from 20 eligible studies. The mean patient age was 82.88
Announcements
Open Access
Systematic Review
Transcatheter Aortic Valve Implantation Outcomes and Challenges in Asia: A Systematic Review and Meta-Analysis
Frederick Berro Rivera1,*, Deogracias Villa De Luna2, Marie Francesca Mapua Ansay3, Ryan T. Nguyen4, Gabrielle Pagdilao Flores5, John Vincent Magalong6, Sung Whoy Cha7, John Paul Aparece7, Jacques Simon T. Gonzales7, Wailea Faye C. Salva7, Gerard Francis E. Mangubat8, Mer Lorraine P. Mahilum8, Taku Inohara9, Krishnaswami Vijayaraghavan10, Fareed Moses S. Collado11, Azeem Latib12
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1
Department of Medicine, Lincoln Medical Center, New York, NY 10451, USA
2
Department of Internal Medicine, Danbury Hospital, Danbury, CT 06810, USA
3
Ateneo de Manila School of Medicine and Public Health, 1604 Pasig, Philippines
4
Department of Medicine, Houston Methodist, Houston, TX 77030, USA
5
King George Hospital, IG3 8YB Ilford, UK
6
Department of Medicine, San Beda University College of Medicine, 1005 Manila, Philippines
7
Cebu Institute of Medicine, 6000 Cebu, Philippines
8
Southern Philippines Medical Center, 8000 Davao, Philippines
9
Department of Cardiology, Keio University School of Medicine, 160-8582 Tokyo, Japan
10
University of Arizona, Tucson, AZ 85721, USA
11
Department of Cardiology, Rush University Medical Center, Chicago, IL 60612, USA
12
Section of Interventional Cardiology-Structural Heart, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY 10461, USA
*Correspondence: frederick.berro.rivera@gmail.com (Frederick Berro Rivera)
Rev. Cardiovasc. Med. 2023, 24(3), 79;
https://doi.org/10.31083/j.rcm2403079
Submitted: 25 November 2022 | Revised: 23 December 2022 | Accepted: 9 January 2023 | Published: 6 March 2023
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract
Keywords
transcatheter
aortic valve
aortic stenosis
TAVR
TAVI
outcomes
Asia
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Fig. 1.