- Academic Editor
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Background: To investigate the incidence of contrast-induced acute
kidney injury (CI-AKI) in patients with acute myocardial infarction (AMI)
undergoing primary percutaneous coronary intervention (PCI) in relation to the
neutrophil to high-density lipoprotein cholesterol ratio (NHR), and to further
compare the predictive value of NHR and the neutrophil to lymphocyte ratio (NLR)
for CI-AKI. Methods: We retrospectively analyzed 1243 AMI patients
undergoing PCI from January 2019 to December 2021, and collected creatinine
within 72 h after PCI. All patients were divided into a CI-AKI group and
non-CI-AKI group according to the definition of CI-AKI, and the clinical
information of the two groups was compared. Potential risk factors for CI-AKI in
AMI patients undergoing primary PCI were screened by using logistic regression
analysis, and receiver operating characteristic (ROC) curves were used to compare
the predictive value of NHR and NLR. Results: A high NHR and high NLR
were correlated with a high incidence of CI-AKI in AMI patients undergoing
primary PCI, and NHR (odds ratio (OR): 1.313, 95% confidence interval (CI):
1.199–1.438) and NLR (OR: 1.105, 95% CI: 1.041–1.174) were independent risk
factors for CI-AKI (p