- Academic Editor
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†These authors contributed equally.
Background: Existing research has shown that retinol binding protein
(RBP4) has an impairing effect on arterial elasticity and induces insulin
resistance, but the clinical value of RBP4 in patients with coronary heart
disease (CHD) combined with type 2 diabetes mellitus (T2DM) has not been
investigated. This study sought to compare the complexity of coronary artery
lesions and coronary artery elasticity between patients with CHD combined with
T2DM and those with CHD without T2DM, analyze the risk factors affecting coronary
artery elasticity, and investigate the value of RBP4 in assessing coronary artery
elasticity in patients with CHD and T2DM. Methods: A total of 130
patients with confirmed CHD were consecutively enrolled, including 38 patients
with CHD combined with T2DM and 92 patients with CHD without T2DM. Basic clinical
data, laboratory findings, coronary angiography and intravascular ultrasound
(IVUS) imaging data, and Gensini scores and coronary artery elasticity parameters
were calculated in both groups. Elasticity parameters included: stiffness
parameter (