†These authors contributed equally.
Background: Several previous studies have explored the potential
arterial blood pressure (BP) changes in patients undergoing right ventricular
pacing (RVP), however, the relationship between left bundle branch area pacing
(LBBAP) and BP variations remains unknown. This study aimed to examine the acute
BP variations following LBBAP and RVP implantation in patients with bradycardia.
Methods: We conducted a single-center retrospective study including all
patients who underwent de-novo dual-chamber pacemaker implantation between
January 2019 and June 2021. Patients were divided into two groups, LBBAP and RVP,
and propensity score-matching (PSM) was used to balance confounding factors.
Three time periods were defined according to the timing of the implant: baseline
(within 24 hours before implantation), hyper-acute period (0–24 hours
post-implantation), and acute period (24–48 hours post-implantation). BP was
measured at least three times per period using an arm pressure cuff and then
averaged for analysis, which allowed us to determine the acute impact of
pacemaker implantation on BP. Results: From a cohort of 898 patients,
193 LBBAP receivers were matched to 193 RVP receivers. A significant decrease in
systolic BP (SBP) after the implantation was observed in the study cohort, from
baseline 137.3