- Academic Editor
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†These authors contributed equally.
Background: Radiofrequency catheter ablation (RFCA) has been shown to
have low efficacy for the treatment of persistent atrial fibrillation (AF) in
patients with hypertrophic cardiomyopathy (HCM). We conducted this study to
evaluate the benefit of adjunctive vein of Marshall (VOM) ethanol infusion during
RFCA for persistent AF (PsAF) in patients with non-obstructive HCM.
Methods: This multicenter retrospective observational study included 102
consecutive non-obstructive HCM patients with PsAF who underwent RFCA plus VOM
ethanol infusion (VOM-EI) (RFCA + VOM, n = 56) or RFCA alone (RFCA, n = 46) for
the first time. The efficacy endpoint was survival without AF or atrial
tachycardia (AT) after the blanking period. Results: We completed the
VOM-EI in 92.9% (52/56) patients. The left pulmonary vein antrum ablation time
(RFCA + VOM: 19.9