Academic Editor: Gernot Riedel
Background: Camptocormia is one of the most common postural disorders
of Parkinson’s disease (PD) which has limited treatment options. In this review,
we summarize the efficacy of deep brain stimulation (DBS) for camptocormia in PD.
Methods: The PubMed (https://pubmed.ncbi.nlm.nih.gov/) and EMBASE
databases (https://www.embase.com/)
were searched for the terms “Parkinson Disease” and “camptocormia” in
combination with “deep brain stimulation”. We then explored the efficacy of DBS
for camptocormia by statistical analysis of the bending angle, the Unified
Parkinson’s Disease Rating Scale III (UPDRS-III) and L-dopa equivalent daily dose
(LEDD), and by evaluating the prognosis after DBS. Results: Twenty
articles that reported results for 152 patients were included in this review.
These comprised 136 patients from 16 studies who underwent subthalamic nucleus
deep brain stimulation (STN-DBS), and 13 patients from 3 studies who underwent
globus pallidus internus deep brain stimulation
(GPi-DBS). One study used both STN-DBS (2
patients) and GPi-DBS (one patient). After 3–21 months of follow-up, the mean
bending angle during the Off-period was significantly reduced compared to pre-DBS
(31.5