- Academic Editor
-
-
-
†These authors contributed equally.
Background: To investigate the diagnostic value of serum transthyretin
(TTR), placental protein 13 (PP13) and placental growth factor (PLGF) in
preeclampsia patients. Methods: Sixty cases of pregnant women with
preeclampsia who were examined in our hospital from January 2020 to February 2022
were retrospectively selected as the preeclampsia group, and 40 cases of healthy
pregnant women who received regular physical examination in our hospital during
the same period were selected as the control group. Based on the severity of the
disease, the patients were allocated into two groups: mild preeclampsia group (n
= 35) and severe preeclampsia group (n = 25). The levels of Serum TTR, PP13 and
PLGF were compared between the groups. The correlation between serum TTR, PP13,
PLGF and the patients was also analyzed by Spearman method, and receiver
operating characteristic curve (ROC) and area under the curve (AUC) was adopted
to analyze the clinical value of the separate and combined detection of serum
TTR, PP13, PLGF in the diagnosis of preeclampsia. Results: The levels of
serum TTR, PP13, PLGF in preeclampsia group were evidently lower versus the
control group (p