- Academic Editor
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Background: The pathogenesis of endometriosis is still debatable, and
many studies reported a predisposition to infectious and immunological factors.
In this study, we aimed to evaluate the human papillomavirus (HPV) positivity in
endometriosis pain-related symptoms and infertility. Methods: In this
cross-sectional study, 410 endometriosis patients were enrolled in this study.
HPV-positive (n = 202) and HPV-negative (n = 208) patients compared with
pain-related symptoms, infertility, and endometrioma presence. The term “Other HPV”
was utilized to encompass all HPV types with the exception of HPV 16 and 18,
which were specifically identified as HPV 16/18. Results: Dyspareunia in
the “Other HPV”-positive group (12.8 %) was statistically higher than in the
HPV-negative group (4.8%; p = 0.007). The infertility rate
was significantly higher in the HPV 16/18 positive group (high-risk HPV) 35.8%
than in the HPV-negative (7.6%), and “Other HPV” positive group (8%; p