- Academic Editor
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Background: Association between second trimester ultrasound
findings and twin pregnancy outcome is still unclear. Study aimed to evaluate the
performance of second trimester ultrasound scan in the prediction of
monochorionic diamniotic twin pregnancies outcomes. Methods:
Prospective-cohort study of all consecutive healthy women with monochorionic twin
pregnancies followed-up and delivered in five years was undertaken. During second
trimester screening (16–18 weeks) fetal biometry was measured (biparietal
diameter–BPD, abdominal circumference–AC, femur length–FL, estimated fetal
weight–EFW) and inter-twin discordance noted. Amniotic fluid amount was
determined. Pregnancy outcomes were having live-born twins, Apgar sores and
birth-weights, pregnancy complications and gestational week of delivery.
Results: Receiver operating characteristics (ROC) analysis showed that
BPD (p = 0.018), AC (p = 0.019) and FL (p = 0.015)
were good predictors of having live-born twins. Regression analysis showed that
the most important factors influencing twins’ survival to term were inter-twin
AC, BPD and FL differences. Fetal discordance in BPD, AC and FL explained
correctly 76.3%, 76.5% and 58% of pregnancy outcomes. If second trimester
inter-twin BPD difference was