- Academic Editors
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Objective: To understand the basic mechanism and dynamic regulation
that underlies the epithelial-to-mesenchymal transition (EMT) in ovarian cancer
(OC) cells. Mechanism: A literature review using evidences from several
data bases (i.e., PubMed, EMBASE, Web of Science, Medline, Cochrane, Science
Direct, and Google Scholar) were conducted to describe the basic mechanism and
dynamic regulation of EMT in OC cells. Finding in Brief: EMT is a
complex epigenetic reprogramming orchestrated by specific transcription factors
(TFs) and multiple upstream activators and regulators, such as transforming
growth factor-