IMR Press / CEOG / Volume 49 / Issue 6 / DOI: 10.31083/j.ceog4906141
Open Access Case Report
Herlyn-Werner-Wunderlich syndrome with double hematocolpos in one side hemivagina
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1 Department of Obstetrics & Gynecology, Chungnam National University Hospital, Chungnam National University School of medicine, 282, Munhwa-ro, 301-721 Jung-gu, Deajeon, Republic of Korea
*Correspondence: (Heon Jong Yoo)
These authors contributed equally.
Academic Editor: Michael H. Dahan
Clin. Exp. Obstet. Gynecol. 2022, 49(6), 141;
Submitted: 6 February 2021 | Revised: 22 February 2021 | Accepted: 12 March 2021 | Published: 10 June 2022
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.

Background: Herlyn-Werner-Wunderlich syndrome (HWWS) is an extremely rare Mullerian anomaly consisting of uterus didelphys with obstructed hemivagina and ipsilateral renal agenesis. Although few HWWS cases had been reported in the gynecological literature, most of the reported cases were combined with single hematocolpos. Case: We report here on a case of HWWS with double hematocolpos on one side of a hemivagina combined with ipsilateral renal agenesis. This is the first report of HWWS with double hematocolpos on one side of a hemivagina that was successfully treated with the resection of the vaginal septum. Conclusion: It is important to understand the pathogenesis and clinical features of these anomalies for diagnosis.

Hereditary renal agenesis
Urogenital abnormalities
Herlyn-Werner-Wunderlich syndrome
Mullerian anomaly
Fig. 1.
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