Academic Editor: Michael H. Dahan
Background: Hyperandrogenism has been associated with tubal
dysfunction. Previous studies have not used non-subfertile controls when
assessing hyperandrogenic women through laparoscopic chromopertubation (LC), the
gold standard for tubal patency testing. Methods: The objective of this
retrospective study was to compare the results of LC between women with
medication-resistant anovulatory polycystic ovary syndrome (PCOS, n = 202) and
non-subfertile women with ovarian cysts (controls, n = 48). Results:
There were no statistically significant differences between PCOS women and
controls for the prevalence of bilateral tubal occlusion (2.5% versus 4.2%,
respectively; p = 1.000) or overall rates for occlusion (7.4% of tubes
assessed versus 6.3%, respectively; p = 0.828). More PCOS patients
needed high pressure chromopertubation to demonstrate bilateral tubal patency
than controls (12.4% versus 2.1%; p = 0.036). In the PCOS group,
patients needing higher pressure to achieve patency demonstrated higher
testosterone levels than women requiring typical pressure (0.66