Academic Editor: Miro Šimun Alebić
Background: Polycystic ovary syndrome (PCOS) affects 3–8% of
adolescents. It is characterized by hyperandrogenism and
oligoovulation/anovulation. PCOS has a negative impact on health-related quality
of life (HRQoL). However, the extents to which factors influence total HRQoL of
adolescents are not known. Adult PCOS patients have a higher incidence of binge
eating than the general reproductive-age female population. Limited data on binge
eating in adolescents with PCOS are available. Aim of this study was to
investigate how PCOS and its associated factors, including binge eating, affect
the HRQoL of adolescent girls. Methods: This case-control study
recruited 63 adolescent girls 13–18 years of age with PCOS and 66 age-matched
healthy controls. The PCOS health-related quality of life questionnaire (PCOSQ)
and Binge Eating Scale (BES) were used. Multiple linear regression was executed
to establish exact predictors and their effect on total HRQoL. Results:
HRQoL was significantly lower in adolescents with PCOS than controls (4.9
(interquartile range (IQR) 1.5) vs. 5.8 (IQR 0.9) points). The
lowest scores were found in the body hair and weight domains. BES results were
not significantly higher in the PCOS group than in the control group (p
= 0.727). The main predictors for total HRQoL were PCOS diagnosis per se
(