Academic Editor: Chia-Hao Liu
Background: Benign leiomyomas (LM) and malignant leiomyosarcomas (LMS)
can be distinguished by increased cellularity with mitotic activity. Uterine
smooth muscle tumors of uncertain malignant potential (STUMP) are a group of rare
tumors in between, for which there is still no standardized classification, nor
any definitive preoperative imaging or laboratory investigations regarding the
possible inclusion of STUMP in the differential diagnosis. Methods: In
this study, we retrospectively reviewed 6 cases of STUMP, and assessed their
pathogenesis, risk factors, and prognostic features. Results: The mean
age of STUMP patients was 40.6 years old. No recurrence has been reported in all
six cases after more than 3.6 years of follow-up. The mean tumor size was 9.44 cm
(range 6.14–12.21). 4 cases (66.7%) with