IMR Press / CEOG / Volume 49 / Issue 10 / DOI: 10.31083/j.ceog4910220
Open Access Review
COVID-19 Vaccination and Pregnancy
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1 Department of Maternal and Child Health, Poznan University of Medical Sciences, 60-535 Poznań, Poland
*Correspondence: natalia.ignaszak@gmail.com (Natalia Ignaszak-Kaus)
These authors contributed equally.
Academic Editor: Shigeki Matsubara
Clin. Exp. Obstet. Gynecol. 2022, 49(10), 220; https://doi.org/10.31083/j.ceog4910220
Submitted: 17 June 2022 | Revised: 12 July 2022 | Accepted: 19 July 2022 | Published: 21 September 2022
(This article belongs to the Special Issue Health Care for Pregnant Women during SARS-CoV-2 Pandemic)
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract

Objectives: A review to assess the safety, efficacy, COVID-19 vaccination acceptance and awareness in pregnant women. Machanism: Pregnant women diagnosed with COVID-19 are characterized by more frequent hospitalization in intensive care units and are at three times higher risk of preterm; their newborns more often need invasive ventilation. Vaccination is the most effective preventive measures against SARS-CoV-2, but there are still questions about safety and immune response. Pregnant women were not included in study groups during phase III clinical trials. Findings in Brief: Vaccination during pregnancy is not associated with an increased risk of obstetric or neonatal complications; scientific communities recommend vaccination for pregnant women, those planning for pregnancy and those who are breastfeeding. Unfortunately, knowledge regarding COVID-19 vaccination and willingness to take vaccine during pregnancy is low. Conclusions: General practitioners and obstetricians have a large role in increasing public awareness of COVID-19 vaccination. No evidence of teratogenicity of the vaccine has been found.

Keywords
COVID-19 vaccination
COVID-19 vaccination and pregnancy
infection of COVID-19 during pregnancy
safety of COVID-19 vaccination
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