Background: A wide variety of studies demonstrate the influence of the
oocyte source’s age on the success of assisted reproduction treatments; however,
the effect of paternal age has been studied to a lesser extent. Therefore, our
goal was to assess the impact of male age and sperm quality on in vitro
fertilization (IVF) outcomes. Methods: Three hundred ninety-four ova
donation IVF cycles from Ingenes México were retrospectively analyzed. All
ova donors (age range: 18–35 years) underwent a similar IVF stimulation
protocol. The oocytes were aspirated and inseminated by intracytoplasmic sperm
injection (ICSI) using either partner sperm (n = 332, age: 42.4
Announcements
Open Access
Original Research
Paternal advanced age and sperm quality are indicators for Preimplantation Genetic Testing in egg donation cycles
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1
Laboratorio de Fertilización in Vitro, Instituto de Infertilidad y Genética México SC, Ingenes, 05320 México City, México
2
Departamento de Toxicología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), 07360 México City, México
*Correspondence: ebayghen@cinvestav.mx (Esther López-Bayghen)
Clin. Exp. Obstet. Gynecol. 2021, 48(6), 1404–1411;
https://doi.org/10.31083/j.ceog4806222
Submitted: 17 March 2021 | Revised: 20 April 2021 | Accepted: 8 June 2021 | Published: 15 December 2021
Copyright: © 2021 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
Abstract
Keywords
Aneuploidy
Egg donor
In vitro fertilization
Paternal age
Preimplantation genetic screening
Funding
250768/Consejo Nacional de Ciencia y Tecnología to ELB
Figures
Fig. 1.