Background: Uterine fibroids are the most common benign gynaecological
tumours in women. When symptomatic, heavy menstrual bleeding is the principal
manifestation of uterine fibroids. Nowadays, several conservative procedures have
been utilized to discourage hysterectomy or myomectomy and great interest has
been focused on laser energy technology associated with mini-invasive approaches.
Diode lasers demonstrated many advantages in laparoscopic and hysteroscopic
surgery. Methods: To evaluate the Dual Wavelength Diode Laser System
(DWLS) ablation techniques for treating fibroids, we devised an experimental
system for characterizing the myolysis fibre ablation performance with a
particular fibre designed to create a thermal ablation in the centre of the
myoma. All the myomas were used for the experiment after a total hysterectomy and
their excision from the fresh uteri. The experiment setup was composed of two
beaker containers filled with isotonic saline water, temperature monitoring myoma
surface and water bath, a diode laser fibre and a diode laser energy deposition
system. Results: Good macroscopic results have been found for fibroids
of about 60 cm
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Ex vivo myolysis with dual wavelengths diode laser system: macroscopic and histopathological examination
Maurizio Nicola D’Alterio1,*, Francesco Scicchitano1, Daniela Fanni2, Gavino Faa2, Antonio Simone Laganà3, Marco Noventa4, Felice Sorrentino5, Luigi Nappi5, Stefano Angioni1
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1
Department of Surgical Sciences, Division of Obstetrics and Gynecology, University of Cagliari, 09124 Cagliari, Italy
2
Department of Medical Sciences and Public Health, Unit of Anatomic Pathology, University of Cagliari, 09124 Cagliari, Italy
3
Department of Obstetrics and Gynecology, “Filippo del Ponte” Hospital, University of Insubria, 21100 Varese, Italy
4
Department of Women and Children’s Health, Clinic of Gynecology and Obstetrics, University of Padua, 35121 Padua, Italy
5
Department of Medical and Surgical Sciences, Institute of Obstetrics and Gynaecology, University of Foggia, 71121 Foggia, Italy
*Correspondence: mauridalte84@gmail.com (Maurizio Nicola D'Alterio)
Clin. Exp. Obstet. Gynecol. 2021, 48(4), 875–882;
https://doi.org/10.31083/j.ceog4804138
Submitted: 7 March 2021 | Revised: 28 March 2021 | Accepted: 9 April 2021 | Published: 15 August 2021
Copyright: © 2021 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
Abstract
Keywords
Uterine fibroids
Myolysis
Diode laser
DWLS
Hysteroscopy
Ex vivo
Figures
Fig. 1.