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Pregnancy outcome after treatment of cervical intraepithelial neoplasia by the loop electrosurgical excision procedure and cold knife conization
1 Research Institute of Oncology (IPON), Discipline of Gynecology and Obstetrics, Federal University of Triangulo Mineiro, Uberaba, MG (Brazil)
Clin. Exp. Obstet. Gynecol. 2009, 36(1), 17–19;
Published: 10 March 2009
Purpose of investigation: The aim of this study was to evaluate the effect of LEEP and cold-knife conization on the outcome of subsequent pregnancy in a tertiary public hospital. Methods: One hundred and ninety-nine patients met the inclusion criteria (age between 18 and 45 years old). Cold-knife conization, LEEP, and both (conization and LEEP) were performed in 102 (51.3%), 95 (47.7%) and two (1%) women, respectively. Average ages were respectively, 33 ± 7.3; 25 ± 6.73 and 30 ± 2.8. Results: Pregnancies occurred 2.6 and 4.8 years after LEEP and conization, respectively. Miscarriages and preterm pregnancies were more frequent in conization cases versus LEEP, 26% and 5.2%, 23% and 5.5%, respectively. Conclusion: If patients express a desire for pregnancy, LEEP should be the procedure of choice.
Cervical intraepithelial neoplasia
Loop electrosurgical excision procedure