Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Artificial endometrial preparation for oocyte donation using synthetic estrogen and progestogen
Objective: To evaluate the outcome of an oocyte donation program using synthetic estrogen and progestational agents for uterine preparation. Methods: Conjugated estrogen, I.25 mg per day at increasing doses and dydrogesterone, a synthetic progestogen, 30 mg per day were used for uterine priming. All embryo transfers were done on day 2 of progestogen supplementation Results: The pregnancy rates were 38% per embryo transfer. The ongoing pregnancy rate was 31 % with an abortion rate of 20%. Conclusion: Endometrial preparation in an oocyte donation program using orally administered synthetic estrogen and progestogen gives pregnancy rates comparable to those reported with natural products.