British Journal of Hospital Medicine (BJHM) is published by IMR Press from Volume 87 Issue 1 (2026). Previous articles were published by another publisher under the hybrid model (CC-BY-NC license or on a subscription basis), and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement.
Biochemical basis of the amyloid diseases
Simon DJ Gibbs 1, Philip N Hawkins 2
Affiliations
Article Info
1 UCL Medical School, Royal Free Hospital Campus, London NW3 2PF
2 National Amyloidosis Centre, UCL Medical School, Royal Free Hospital Campus, London NW3 2PF
Abstract
Amyloidosis is a heterogeneous group of diseases characterized by normally soluble proteins deposited extracellularly in an abnormally folded, insoluble fibrillar form. This can lead to organ impairment and premature death. This article discusses the pathogenesis, classification system and means of diagnosis of the amyloid diseases.