Dear Colleagues,

This Special Issue of the International Journal of Pharmacology aims to showcase significant scientific advances in the field of natural bioactive molecules, with a specific focus on their pharmacological relevance, mechanisms of action, and therapeutic potential.

We invite submissions of original research articles that explore bioactive compounds derived from natural sources, including plants, fungi, marine organisms, and microorganisms. A key requirement is that studies on extraction, isolation, and chemical characterization must be directly linked to demonstrable pharmacological outcomes.

Priority will be accorded to research providing strong mechanistic insights. We particularly encourage studies involving:

Investigation of molecular interactions, signaling pathway modulation, and target engagement.

Comprehensive pharmacodynamic and pharmacokinetic analyses.

Demonstration of efficacy is validated in vitro or in vivo disease models.

Furthermore, submissions employing innovative approaches are highly welcome. These include, but are not limited to, advanced encapsulation strategies, natural drug delivery systems, biotechnological optimization, and computational pharmacology (e.g., molecular docking, dynamics, and predictive modeling), especially when these approaches substantiate the therapeutic applicability of the compounds studied.

Prof. Dr. Mozaniel Santana de Oliveira
Guest Editor