IMR Press / FBL / Volume 13 / Issue 11 / DOI: 10.2741/2993

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Non-synaptic neuronal mechanisms of learning and memory in gastropod molluscs
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1 Sussex Centre for Neuroscience, School of Life Sciences, University of Sussex, Falmer, Brighton, East Sussex, BN1 9QG, U.K.

*Author to whom correspondence should be addressed.

Academic Editor: Anna Di Cosmo

Front. Biosci. (Landmark Ed) 2008, 13(11), 4051–4057;
Published: 1 May 2008
(This article belongs to the Special Issue Developmental and neuronal plasticity)

Gastropod molluscs provide important model systems for investigating the behavioral and neural basis of associative and non-associative learning. Habituation, sensitization, classical and operant conditioning are studied in motor reflex and central pattern generator circuits. Although synaptic plasticity has long been recognized as playing a key role in molluscan learning circuits, non-synaptic changes resulting in alterations in the excitability of neurons are increasingly recognized as an essential component of the memory trace.

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