Advances in congenital heart disease (CHD) have radically changed the prognosis and burden of the disease. More than 90% of patients with CHD are now surviving to adulthood and adults account for over two-thirds of the contemporary CHD population in Western countries. Although outcomes have improved, surgery does not cure CHD. Decades of longitudinal observational data are currently motivating a paradigm shift toward a lifespan perspective and proactive approach to CHD care. Multimodality imaging and other biomarkers are paramount in diagnosing and reliably evaluating the severity of structural complications that may arise over the lifespan. Furthermore, advances in the field of interventional therapies have enabled management of multiple defects and complications, obviating the need for an open-heart surgery. Despite all the progress made over the years, there are still patients with increased morbidity burden who require close follow-up and a multidisciplinary team approach to deal with multi-system complications. Finally, early evaluation for transplantation is also important for patients with advanced heart failure. In this Special Issue "Adult congenital heart disease: diagnosis, prognosis and management", we aim to publish papers that focus on all current issues of adult patients with congenital heart disease that include but are not limited to:
1. Diagnostic methods in ACHD
2. Multimodality imaging in ACHD
3. Biomarkers in ACHD
4. Prognostic tools in ACHD
5. Therapeutic approach in ACHD
6. Management of multisystem complications in ACHD
7. Interventional procedures and devices in ACHD
8. Management of ACHD comorbidities
Prof. George Giannakoulas and Dr. Alexandra Arvanitaki
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